BDBM50088703 CHEMBL12603::N-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-ethyl}-2-(2-oxo-azepan-1-yl)-acetamide::RWJ-68157

SMILES CC(C)Oc1ccccc1N1CCN(CCNC(=O)CN2CCCCCC2=O)CC1

InChI Key InChIKey=XHBOWUOETHUEOP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50088703   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088703(CHEMBL12603 | N-{2-[4-(2-Isopropoxy-phenyl)-pipera...)
Affinity DataKi:  18nMAssay Description:Binding affinity for human Alpha-1A adrenergic receptor expressed in COS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088703(CHEMBL12603 | N-{2-[4-(2-Isopropoxy-phenyl)-pipera...)
Affinity DataKi:  22nMAssay Description:Binding constant measured against Alpha-1A adrenergic receptor in human prostate; ++:moderately activeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088703(CHEMBL12603 | N-{2-[4-(2-Isopropoxy-phenyl)-pipera...)
Affinity DataKi:  505nMAssay Description:Binding affinity for human Alpha-1D adrenergic receptor expressed in COS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088703(CHEMBL12603 | N-{2-[4-(2-Isopropoxy-phenyl)-pipera...)
Affinity DataKi:  3.54E+3nMAssay Description:Binding affinity for human Alpha-1B adrenergic receptor expressed in COS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed