BDBM50089653 CHEMBL3576974

SMILES Cc1ccc(cc1)S(=O)(=O)n1cc(C(=O)C(=O)NCC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(O)=O)c2ccccc12

InChI Key

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50089653   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50089653(CHEMBL3576974)
Affinity DataKi:  5nMAssay Description:Competitive inhibition of human recombinant COX-2 by UV-Visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50089653(CHEMBL3576974)
Affinity DataIC50:  4.35E+4nMAssay Description:Inhibition of ovine COX-1 assessed as PGF2alpha formation using arachidonic acid as substrate pretreated with compound for 20 mins prior to substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50089653(CHEMBL3576974)
Affinity DataIC50:  99nMAssay Description:Inhibition of human recombinant COX-2 assessed as PGF2 alpha formation using arachidonic acid as substrate pretreated with compound for 20 mins prior...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed