BDBM86213 CAS_5126051::CHEMBL327783::CPCCOEt::NSC_5126051

SMILES CCOC(=O)C12CC1C(N=O)c1ccccc1O2

InChI Key InChIKey=FINYWNDRBPWDDL-UHFFFAOYSA-N

Data  8 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 86213   

TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 1(Rat)
Johnson and Johnson Pharmaceutical Research and Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051)
Affinity DataKi:  4.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051)
Affinity DataKi:  9.90E+3nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051)
Affinity DataKi: >1.00E+5nMAssay Description:Antagonist potency against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 4(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 8(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 7(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 7 (mGluR-7).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051)
Affinity DataIC50:  6.60E+3nMAssay Description:Antagonist activity at human mGlu1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051)
Affinity DataIC50:  2.30E+4nMAssay Description:Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article

TargetMetabotropic glutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glutamate receptor 1 Expressing CellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed