BDBM50090057 1-Phenyl-1,6-dihydro-[1,3,5]triazine-2,4-diamine::CHEMBL92846
SMILES NC1=NCN(C(N)=N1)c1ccccc1
InChI Key InChIKey=RLKGBZALMDTISP-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50090057
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
Università
Curated by ChEMBL
Università
Curated by ChEMBL
Affinity DataKi: 85nMAssay Description:Inhibition constant against Plasmodium falciparum dihydrofolate reductaseChecked by AuthorMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum)
National Center For Genetic Engineering And Biotechnology At Thailand
Curated by ChEMBL
National Center For Genetic Engineering And Biotechnology At Thailand
Curated by ChEMBL
Affinity DataKi: 329nMAssay Description:Evaluated for inhibition constant (Ki wt) against Wild-type dihydrofolate reductase of Plasmodium falciparumMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [A16V,S108T](Plasmodium falciparum)
National Center For Genetic Engineering And Biotechnology At Thailand
Curated by ChEMBL
National Center For Genetic Engineering And Biotechnology At Thailand
Curated by ChEMBL
Affinity DataKi: 585nMAssay Description:Inhibition constant (Ki mut) against A16V+S108T Mutant DHFRs of Plasmodium falciparumMore data for this Ligand-Target Pair