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BDBM50090283 2-Diphenylacetylamino-5-guanidino-pentanoic acid ((S)-1-phenyl-ethyl)-amide::CHEMBL433627

SMILES: C[C@H](NC(=O)C(CCCNC(N)=N)NC(=O)C(c1ccccc1)c1ccccc1)c1ccccc1

InChI Key: InChIKey=JWTLMJAUZBYAPO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090283   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))
BDBM50090283
PNG
(2-Diphenylacetylamino-5-guanidino-pentanoic acid (...)
Show SMILES C[C@H](NC(=O)C(CCCNC(N)=N)NC(=O)C(c1ccccc1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H33N5O2/c1-20(21-12-5-2-6-13-21)32-26(34)24(18-11-19-31-28(29)30)33-27(35)25(22-14-7-3-8-15-22)23-16-9-4-10-17-23/h2-10,12-17,20,24-25H,11,18-19H2,1H3,(H,32,34)(H,33,35)(H4,29,30,31)
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Similars

Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
NPY Y1-antagonistic activity in HEL cells by measuring the inhibition of porcine NPY (10 nM) stimulated increase in the intracellular [Ca2+] concentr...


Bioorg Med Chem Lett 10: 1597-600 (2000)


Article DOI: 10.1016/s0960-894x(00)00292-4
BindingDB Entry DOI: 10.7270/Q2HD7TWN
More data for this
Ligand-Target Pair