BDBM50091555 CHEMBL3582307

SMILES Fc1ccc(cc1)-c1c[nH]c(n1)[C@H]1Cc2c(CN1)[nH]c1ccccc21

InChI Key

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091555   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091555(CHEMBL3582307)
Affinity DataKi:  290nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091555(CHEMBL3582307)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]SS-14 from human recombinant SSTR3 expressed in CHO cell membranes incubated for 60 to 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091555(CHEMBL3582307)
Affinity DataIC50:  15nMAssay Description:Antagonist activity against human recombinant SSTR3 expressed in CHO cells assessed as reduction in forskolin-induced cAMP accumulation in presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed