BDBM50091732 (S)-3-(2-{(R)-3-[2-(2-Amino-pyridin-4-yl)-ethyl]-2-oxo-piperidin-1-yl}-acetylamino)-pent-4-ynoic acid::CHEMBL57192

SMILES Nc1cc(CC[C@@H]2CCCN(CC(=O)N[C@@H](CC(O)=O)C#C)C2=O)ccn1

InChI Key InChIKey=KRMFBDFPPIORKF-LSDHHAIUSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091732   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091732((S)-3-(2-{(R)-3-[2-(2-Amino-pyridin-4-yl)-ethyl]-2...)
Affinity DataKd:  340nMAssay Description:Binding affinity to resting form of alpha IIb/beta3 integrin by flow cytometry using fluorescein ligand L-726,745 displacement from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091732((S)-3-(2-{(R)-3-[2-(2-Amino-pyridin-4-yl)-ethyl]-2...)
Affinity DataKd:  0.780nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091732((S)-3-(2-{(R)-3-[2-(2-Amino-pyridin-4-yl)-ethyl]-2...)
Affinity DataIC50:  28nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed