BDBM50092161 CHEMBL3582455

SMILES Fc1ccc2nc(-c3cccnc3)n(CC(F)(F)F)c2c1

InChI Key InChIKey=XMYULAQRJPNVOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092161   

TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092161(CHEMBL3582455)
Affinity DataIC50:  561nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092161(CHEMBL3582455)
Affinity DataIC50: >8.33E+3nMAssay Description:Inhibition of human CYP11B1 expressed in V79 cells incubated for 1 hr before 11-deoxycortisol substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed