BDBM50092671 CHEMBL125742::N,N-Diethyl-4-[(3-methoxy-phenyl)-piperazin-1-yl-methyl]-benzamide

SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCNCC1)c1cccc(OC)c1

InChI Key InChIKey=ABHGGPDVTGXLFS-UHFFFAOYSA-N

Data  3 IC50  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50092671   

TargetDelta-type opioid receptor(Homo sapiens (Human))
AstraZeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092671(CHEMBL125742 | N,N-Diethyl-4-[(3-methoxy-phenyl)-p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCNCC1)c1cccc(OC)c1
Show InChI InChI=1S/C23H31N3O2/c1-4-25(5-2)23(27)19-11-9-18(10-12-19)22(26-15-13-24-14-16-26)20-7-6-8-21(17-20)28-3/h6-12,17,22,24H,4-5,13-16H2,1-3H3
Affinity DataIC50: 25nMAssay Description:Binding affinity against human opioid receptor delta 1 using [125I]-[D-Ala2]-deltorphin II as radioligandMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
AstraZeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092671(CHEMBL125742 | N,N-Diethyl-4-[(3-methoxy-phenyl)-p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCNCC1)c1cccc(OC)c1
Show InChI InChI=1S/C23H31N3O2/c1-4-25(5-2)23(27)19-11-9-18(10-12-19)22(26-15-13-24-14-16-26)20-7-6-8-21(17-20)28-3/h6-12,17,22,24H,4-5,13-16H2,1-3H3
Affinity DataIC50: 5.29E+3nMAssay Description:Binding affinity against cloned human Opioid receptor mu 1 using [125I]FK33824 as radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092671(CHEMBL125742 | N,N-Diethyl-4-[(3-methoxy-phenyl)-p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCNCC1)c1cccc(OC)c1
Show InChI InChI=1S/C23H31N3O2/c1-4-25(5-2)23(27)19-11-9-18(10-12-19)22(26-15-13-24-14-16-26)20-7-6-8-21(17-20)28-3/h6-12,17,22,24H,4-5,13-16H2,1-3H3
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against cloned human Opioid receptor kappa 1 using [125I]-D-Pro10-dynorphin A[1-11] as radioligandMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
AstraZeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092671(CHEMBL125742 | N,N-Diethyl-4-[(3-methoxy-phenyl)-p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCNCC1)c1cccc(OC)c1
Show InChI InChI=1S/C23H31N3O2/c1-4-25(5-2)23(27)19-11-9-18(10-12-19)22(26-15-13-24-14-16-26)20-7-6-8-21(17-20)28-3/h6-12,17,22,24H,4-5,13-16H2,1-3H3
Affinity DataEC50:  42nMAssay Description:Agonist potency was measured using GTP gamma-[35S] binding assayMore data for this Ligand-Target Pair