BDBM50094191 17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol::CHEMBL341591

SMILES CC12CCC3C(CC=C4CC(O)CCC34C)C1CCC2CC1CN1

InChI Key InChIKey=KRFWHRJXDKUGAA-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50094191   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataKi:  6nMAssay Description:Binding affinity for Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataKi:  9nMAssay Description:Binding affinity for Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataIC50:  530nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of thromboxane synthase P450 TXA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of P450 sccMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataIC50:  400nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed