BDBM50094503 2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-indole-5-carbonitrile::2-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile::CHEMBL143761

SMILES Fc1ccc(cc1)N1CCN(Cc2cc3cc(ccc3[nH]2)C#N)CC1

InChI Key InChIKey=VEYSGMPQWOSGTB-UHFFFAOYSA-N

Data  10 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50094503   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094503(2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-in...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D4.4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094503(2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-in...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094503(2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-in...)
Affinity DataKi:  8.60E+3nMAssay Description:Binding affinity against Dopamine receptor D1 from bovine striatal membranes using [3H]SCH-23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Sus scrofa)
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50094503(2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-in...)
Affinity DataKi:  8.60E+3nMAssay Description:Displacement of [3H]SCH 23990 from dopamine receptor D1 in porcine striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50094503(2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-in...)
Affinity DataKi:  1.50E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D3 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50094503(2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-in...)
Affinity DataKi:  1.50E+4nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50094503(2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-in...)
Affinity DataKi:  1.90E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(short) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50094503(2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-in...)
Affinity DataKi:  1.90E+4nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2S expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50094503(2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-in...)
Affinity DataKi:  2.80E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(long) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50094503(2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-in...)
Affinity DataKi:  2.80E+4nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094503(2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-in...)
Affinity DataEC50:  9.40nMAssay Description:Effective dose was measured by the stimulation of mitogenesis at dopamine D4.2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed