BDBM50094519 (R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,2,2-tetrafluoro-ethoxy)-benzyl]-amino}-propan-2-ol::(R)-1,1,1-trifluoro-3-((3-phenoxyphenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)propan-2-ol::(R)-3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-phenoxyphenyl)amino)-1,1,1-trifluoropropan-2-ol::1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,2,2-tetrafluoro-ethoxy)-benzyl]-amino}-propan-2-ol::CHEMBL303954::SC-795
SMILES O[C@H](CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccccc2)c1)C(F)(F)F
InChI Key InChIKey=XNYMOOHZPFZFJE-OAQYLSRUSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50094519
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human CETP-mediated transfer of [3H]-CE from HDL to LDLMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Tested for inhibiting CETP-mediated transfer of [3H]-CE from HDL to LDL in vitro under buffered assay conditions in human serum.More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of cholesteryl ester transfer protein in presence of human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+5nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of CETP in human whole plasmaMore data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Oryctolagus cuniculus)
Al-Zaytoonah Private University Of Jordan
Curated by ChEMBL
Al-Zaytoonah Private University Of Jordan
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of CETP assessed as transfer of [3H]cholesterol esters from HDL to LDLMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human CETP assessed as transfer of [3H]cholesterol esters from HDL to LDL in humna plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human CETP by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair