BDBM50094524 (R)-1,1,1-trifluoro-3-((3-(trifluoromethylthio)benzyl)(3,4,5-trimethoxyphenyl)amino)propan-2-ol::1,1,1-Trifluoro-3-[(3-trifluoromethylsulfanyl-benzyl)-(3,4,5-trimethoxy-phenyl)-amino]-propan-2-ol::CHEMBL126074

SMILES COc1cc(cc(OC)c1OC)N(C[C@@H](O)C(F)(F)F)Cc1cccc(SC(F)(F)F)c1

InChI Key InChIKey=PKXHKSUTOFGDQB-QGZVFWFLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094524   

TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094524((R)-1,1,1-trifluoro-3-((3-(trifluoromethylthio)ben...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant human CETP-mediated transfer of [3H]-CE from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Oryctolagus cuniculus)
Al-Zaytoonah Private University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50094524((R)-1,1,1-trifluoro-3-((3-(trifluoromethylthio)ben...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094524((R)-1,1,1-trifluoro-3-((3-(trifluoromethylthio)ben...)
Affinity DataIC50:  5.00E+3nMAssay Description:Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed