BDBM50096062 5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-pentanoic acid::CHEMBL135504

SMILES Cc1c(O)c2cccc(O)c2c(O)c1C=CCCC(O)=O

InChI Key InChIKey=UJWPIYJOLWFFBE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096062   

TargetTrypanothione reductase(Trypanosoma cruzi)
Umr 8525 Cnrs - Université

Curated by ChEMBL
LigandPNGBDBM50096062(5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Umr 8525 Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50096062(5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro inhibition of Plasmodium falciparum Glutathione ReductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Umr 8525 Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50096062(5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of human Glutathione ReductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed