BDBM50097343 3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-4H-benzo[f][1,4]oxazepin-5-one::CHEMBL347167
SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ncccn1
InChI Key InChIKey=MTXWTNUNMLDZTE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50097343
Affinity DataIC50: 199nMAssay Description:Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 199nMAssay Description:Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research
Curated by ChEMBL
Daiichi Suntory Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.59nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research
Curated by ChEMBL
Daiichi Suntory Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair