BindingDB logo
myBDB logout

BDBM50097482 CHEMBL3585854

SMILES: C[C@H](Cc1ccc(NCc2cc(F)ccc2O)cc1)N(C)CC#C

InChI Key: InChIKey=UEMDIVVGGXLWPI-OAHLLOKOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097482   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50097482
PNG
(CHEMBL3585854)
Show SMILES C[C@H](Cc1ccc(NCc2cc(F)ccc2O)cc1)N(C)CC#C
Show InChI InChI=1S/C20H23FN2O/c1-4-11-23(3)15(2)12-16-5-8-19(9-6-16)22-14-17-13-18(21)7-10-20(17)24/h1,5-10,13,15,22,24H,11-12,14H2,2-3H3/t15-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-B using benzylamine as substrate incubated for 15 mins prior to substrate addition measured after 20 mins by fluo...


Bioorg Med Chem 23: 3722-9 (2015)


Article DOI: 10.1016/j.bmc.2015.04.009
BindingDB Entry DOI: 10.7270/Q2S46TQR
More data for this
Ligand-Target Pair