BDBM50098716 CHEMBL3593332

SMILES CC(C)(C)c1cc(no1)C(=O)C(=N\Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)\C#N

InChI Key InChIKey=AASAPGKFLXGPST-UVHMKAGCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50098716   

TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50098716(CHEMBL3593332)
Affinity DataIC50:  5.70E+3nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50098716(CHEMBL3593332)
Affinity DataIC50:  6.40E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed