BDBM50098760 (E)-1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(1H-indol-5-ylsulfanyl)-phenyl]-propenone::1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(1H-indol-5-ylsulfanyl)-phenyl]-propenone::CHEMBL19913

SMILES CC(=O)N1CCN(CC1)C(=O)\C=C\c1ccc(Sc2ccc3[nH]ccc3c2)c(Cl)c1

InChI Key InChIKey=SWIQOJQBTDWCRB-XVNBXDOJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50098760   

TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098760((E)-1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(1H-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Leukocyte function associated antigen 1 (LFA-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098760((E)-1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(1H-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1, range (20-30)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed