BDBM50098853 2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyrimidin-1-yl]-acetylamino}-3-phenyl-propionyl)-benzooxazole-5-carboxylic acid methyl ester::CHEMBL26285

SMILES COC(=O)c1ccc2oc(nc2c1)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(ncc(N)c1=O)-c1cccc(OC)c1

InChI Key InChIKey=JBVRJKUPBUZDDJ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50098853   

TargetChymase(Homo sapiens (Human))
Welfide

Curated by ChEMBL
LigandPNGBDBM50098853(2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...)
Affinity DataKi:  1.12nMAssay Description:Inhibitory activity against canine skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Welfide

Curated by ChEMBL
LigandPNGBDBM50098853(2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...)
Affinity DataKi:  4.85nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast cell protease 9(Mus musculus)
Welfide

Curated by ChEMBL
LigandPNGBDBM50098853(2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...)
Affinity DataKi:  63.9nMAssay Description:Inhibitory activity against mouse peritoneal chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Rattus norvegicus)
Welfide

Curated by ChEMBL
LigandPNGBDBM50098853(2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...)
Affinity DataKi:  86.6nMAssay Description:Inhibitory activity against rat peritoneal chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Welfide

Curated by ChEMBL
LigandPNGBDBM50098853(2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...)
Affinity DataKi:  379nMAssay Description:Inhibitory activity against human cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Welfide

Curated by ChEMBL
LigandPNGBDBM50098853(2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...)
Affinity DataKi:  943nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed