BDBM50099135 1-{2-[2,3-Dichloro-4-(2-isopropyl-phenylsulfanyl)-phenyl]-cyclopropanecarbonyl}-piperidine-4-carboxylic acid::CHEMBL367084

SMILES CC(C)c1ccccc1Sc1ccc(C2CC2C(=O)N2CCC(CC2)C(O)=O)c(Cl)c1Cl

InChI Key InChIKey=MEMSOGHDJLMQDL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099135   

TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50099135(1-{2-[2,3-Dichloro-4-(2-isopropyl-phenylsulfanyl)-...)
Affinity DataIC50:  9nMAssay Description:Ability to block the adherence of leukocyte function-associated antigen-1 (LFA-1) expressing JY-8 cells and intercellular adhesion molecule (ICAM-1) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50099135(1-{2-[2,3-Dichloro-4-(2-isopropyl-phenylsulfanyl)-...)
Affinity DataIC50:  9nMAssay Description:50% inhibition of JY-8 cell adhesion to ICAM-1 via leukocyte function-associated antigen-1 (LFA-1) with 50% FBSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed