BDBM50099700 CHEMBL51776::N-[7-(3-Methoxycarbonyl-propionylamino)-9,10-dioxo-9,10-dihydro-phenanthren-2-yl]-succinamic acid methyl ester

SMILES COC(=O)CCC(=O)Nc1ccc-2c(c1)C(=O)C(=O)c1cc(NC(=O)CCC(=O)OC)ccc-21

InChI Key InChIKey=GKNYSTDFDJPKOW-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50099700   

TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(CHEMBL51776 | N-[7-(3-Methoxycarbonyl-propionylami...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(CHEMBL51776 | N-[7-(3-Methoxycarbonyl-propionylami...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against FAP-1 using lck-10 mer as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(CHEMBL51776 | N-[7-(3-Methoxycarbonyl-propionylami...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(CHEMBL51776 | N-[7-(3-Methoxycarbonyl-propionylami...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against Cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(CHEMBL51776 | N-[7-(3-Methoxycarbonyl-propionylami...)
Affinity DataIC50:  300nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10 mer as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(CHEMBL51776 | N-[7-(3-Methoxycarbonyl-propionylami...)
Affinity DataIC50:  300nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10 mer as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(CHEMBL51776 | N-[7-(3-Methoxycarbonyl-propionylami...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibitory concentration against Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(CHEMBL51776 | N-[7-(3-Methoxycarbonyl-propionylami...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory concentration against FAP-1 pNPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed