BDBM50099714 CHEMBL50846::N-(9,10-Dioxo-9,10-dihydro-phenanthren-3-yl)-butyramide

SMILES CCCC(=O)Nc1ccc2C(=O)C(=O)c3ccccc3-c2c1

InChI Key InChIKey=XRHJCLBIDQJFKO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099714   

TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099714(CHEMBL50846 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099714(CHEMBL50846 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against PTP1B using lck as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099714(CHEMBL50846 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10 mer as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed