BDBM50099891 3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL283036

SMILES FC(F)(F)c1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1

InChI Key InChIKey=BFQIOOYNLCWKIJ-UHFFFAOYSA-N

Data  23 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50099891   

TargetD(4) dopamine receptor(RAT)
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi:  34nMAssay Description:In vitro binding affinity to rat Dopamine receptor D4 measured by displacement of the radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi:  318nMAssay Description:In vitro binding affinity to human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi:  2.79E+3nMAssay Description:Binding affinity to cloned human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi:  7.11E+3nMAssay Description:In vitro binding affinity to human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned human 5-hydroxytryptamine 1E receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned human 5-hydroxytryptamine 5A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of the compound to cloned Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity to rat Dopamine receptor D2 measured by displacement of the radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity to human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Muscarinic acetylcholine receptor M5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(RAT)
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity to cloned rat D5 receptor measured by displacement of radioligand [3H]-SCH-23,982More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity to cloned rat Dopamine receptor D3 measured by displacement of the radioligand [3H]-sulpirideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity to cloned rat Dopamine receptor D1 measured by displacement of radioligand [3H]-SCH-23,982More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50099891(3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Muscarinic acetylcholine receptor M4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed