BDBM50100204 7-Chloro-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-quinazoline-2,4-dione::CHEMBL60471

SMILES COc1cccc2[C@@H]3CN(CCn4c(=O)[nH]c5cc(Cl)ccc5c4=O)C[C@@H]3CCc12

InChI Key InChIKey=YBNNEESMGJJPKH-IFXJQAMLSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100204   

TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100204(7-Chloro-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-b...)
Affinity DataKi:  0.570nMAssay Description:Binding affinity to alpha-1A adrenergic receptor in rat submaxillary glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100204(7-Chloro-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-b...)
Affinity DataKi:  0.580nMAssay Description:Binding affinity of the compound to rat alpha-1D adrenergic receptor expressed in LTK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100204(7-Chloro-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-b...)
Affinity DataKi:  2.71nMAssay Description:Binding affinity to hamster alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed