BDBM50101610 2-Amino-1-{3-[(2,2-dimethyl-propylamino)-methyl]-3,4-dihydro-1H-isoquinolin-2-yl}-3-(4-hydroxy-2,6-dimethyl-phenyl)-propan-1-one::CHEMBL76573

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1CNCC(C)(C)C

InChI Key InChIKey=LSZXSXIVNDQCSM-URXFXBBRSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50101610   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101610(2-Amino-1-{3-[(2,2-dimethyl-propylamino)-methyl]-3...)
Affinity DataEC50:  1.40nMAssay Description:Agonist potency using GTP-gamma [35S]- binding assay for opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101610(2-Amino-1-{3-[(2,2-dimethyl-propylamino)-methyl]-3...)
Affinity DataEC50:  2.80nMAssay Description:Agonist potency using GTP-gamma [35S]- binding assay for delta-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101610(2-Amino-1-{3-[(2,2-dimethyl-propylamino)-methyl]-3...)
Affinity DataIC50:  1.5nMAssay Description:Agonist potency using GTP-gamma [35S]- binding assay for opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101610(2-Amino-1-{3-[(2,2-dimethyl-propylamino)-methyl]-3...)
Affinity DataIC50:  1.30nMAssay Description:Agonist potency using GTP-gamma [35S]- binding assay for mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101610(2-Amino-1-{3-[(2,2-dimethyl-propylamino)-methyl]-3...)
Affinity DataIC50:  0.990nMAssay Description:Binding affinity at cloned human delta-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed