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BDBM50101741 CHEMBL3394896

SMILES: CNc1ccc(cc1)C(=O)N\N=C\c1cc(Br)c(O)c(OC)c1

InChI Key: InChIKey=WQBIAJULZLHSGN-DJKKODMXSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101741   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone chaperone ASF1A


(Homo sapiens (Human))
BDBM50101741
PNG
(CHEMBL3394896)
Show SMILES CNc1ccc(cc1)C(=O)N\N=C\c1cc(Br)c(O)c(OC)c1
Show InChI InChI=1S/C16H16BrN3O3/c1-18-12-5-3-11(4-6-12)16(22)20-19-9-10-7-13(17)15(21)14(8-10)23-2/h3-9,18,21H,1-2H3,(H,20,22)/b19-9+
PDB

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UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.70E+4n/an/an/an/an/an/a



Colorado State University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay


Bioorg Med Chem Lett 25: 963-8 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.067
BindingDB Entry DOI: 10.7270/Q2VM4F0G
More data for this
Ligand-Target Pair