BDBM50102085 1-Amino-3-[4-(3-chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-propan-2-ol::CHEMBL56502

SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCC(O)CN

InChI Key InChIKey=AYMHYBUGFXYGNZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102085   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102085(1-Amino-3-[4-(3-chloro-4-fluoro-phenylamino)-7-met...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed