BDBM50102330 2-(4-(3-(benzo[b]thiophen-3-yl)-3-hydroxypropyl)piperazin-1-yl)phenol::2-[4-(3-Benzo[b]thiophen-3-yl-3-hydroxy-propyl)-piperazin-1-yl]-phenol::CHEMBL135890

SMILES OC(CCN1CCN(CC1)c1ccccc1O)c1csc2ccccc12

InChI Key InChIKey=ABYMPOVMMYXTTE-UHFFFAOYSA-N

Data  4 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102330   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad de Navarra

Curated by ChEMBL
LigandPNGBDBM50102330(2-(4-(3-(benzo[b]thiophen-3-yl)-3-hydroxypropyl)pi...)
Show SMILES OC(CCN1CCN(CC1)c1ccccc1O)c1csc2ccccc12
Show InChI InChI=1S/C21H24N2O2S/c24-19(17-15-26-21-8-4-1-5-16(17)21)9-10-22-11-13-23(14-12-22)18-6-2-3-7-20(18)25/h1-8,15,19,24-25H,9-14H2
Affinity DataKi:  18nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade Federal da Para£ba

Curated by ChEMBL
LigandPNGBDBM50102330(2-(4-(3-(benzo[b]thiophen-3-yl)-3-hydroxypropyl)pi...)
Show SMILES OC(CCN1CCN(CC1)c1ccccc1O)c1csc2ccccc12
Show InChI InChI=1S/C21H24N2O2S/c24-19(17-15-26-21-8-4-1-5-16(17)21)9-10-22-11-13-23(14-12-22)18-6-2-3-7-20(18)25/h1-8,15,19,24-25H,9-14H2
Affinity DataKi:  18.2nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade Federal da Para£ba

Curated by ChEMBL
LigandPNGBDBM50102330(2-(4-(3-(benzo[b]thiophen-3-yl)-3-hydroxypropyl)pi...)
Show SMILES OC(CCN1CCN(CC1)c1ccccc1O)c1csc2ccccc12
Show InChI InChI=1S/C21H24N2O2S/c24-19(17-15-26-21-8-4-1-5-16(17)21)9-10-22-11-13-23(14-12-22)18-6-2-3-7-20(18)25/h1-8,15,19,24-25H,9-14H2
Affinity DataKi:  18.2nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad de Navarra

Curated by ChEMBL
LigandPNGBDBM50102330(2-(4-(3-(benzo[b]thiophen-3-yl)-3-hydroxypropyl)pi...)
Show SMILES OC(CCN1CCN(CC1)c1ccccc1O)c1csc2ccccc12
Show InChI InChI=1S/C21H24N2O2S/c24-19(17-15-26-21-8-4-1-5-16(17)21)9-10-22-11-13-23(14-12-22)18-6-2-3-7-20(18)25/h1-8,15,19,24-25H,9-14H2
Affinity DataKi:  39nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair