BDBM50102787 2-(2-Hydroxy-3-nitro-phenyl)-1H-benzoimidazole-5-carboxamidine::CHEMBL327789

SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cccc(c1O)[N+]([O-])=O

InChI Key InChIKey=OTAHRUQGGGHPEP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102787   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102787(2-(2-Hydroxy-3-nitro-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataKi:  900nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102787(2-(2-Hydroxy-3-nitro-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102787(2-(2-Hydroxy-3-nitro-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102787(2-(2-Hydroxy-3-nitro-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102787(2-(2-Hydroxy-3-nitro-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102787(2-(2-Hydroxy-3-nitro-phenyl)-1H-benzoimidazole-5-c...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed