BDBM50104001 4-(benzylthio)-N-hydroxy-2-(N-isobutyl-4-methoxyphenylsulfonamido)butanamide::4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-butyramide::CHEMBL104022

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)C(CCSCc1ccccc1)C(=O)NO

InChI Key InChIKey=TWQZYQBXMVVVCY-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50104001   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50104001(4-(benzylthio)-N-hydroxy-2-(N-isobutyl-4-methoxyph...)
Affinity DataIC50: <0.100nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50104001(4-(benzylthio)-N-hydroxy-2-(N-isobutyl-4-methoxyph...)
Affinity DataIC50: <0.100nMAssay Description:Binding affinity to MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50104001(4-(benzylthio)-N-hydroxy-2-(N-isobutyl-4-methoxyph...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50104001(4-(benzylthio)-N-hydroxy-2-(N-isobutyl-4-methoxyph...)
Affinity DataIC50:  104nMAssay Description:In vitro inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50104001(4-(benzylthio)-N-hydroxy-2-(N-isobutyl-4-methoxyph...)
Affinity DataIC50:  12nMAssay Description:Binding affinity to MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50104001(4-(benzylthio)-N-hydroxy-2-(N-isobutyl-4-methoxyph...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50104001(4-(benzylthio)-N-hydroxy-2-(N-isobutyl-4-methoxyph...)
Affinity DataIC50:  104nMAssay Description:Binding affinity to MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50104001(4-(benzylthio)-N-hydroxy-2-(N-isobutyl-4-methoxyph...)
Affinity DataIC50:  0.700nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50104001(4-(benzylthio)-N-hydroxy-2-(N-isobutyl-4-methoxyph...)
Affinity DataIC50:  0.700nMAssay Description:Binding affinity to MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50104001(4-(benzylthio)-N-hydroxy-2-(N-isobutyl-4-methoxyph...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibition of human matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed