BDBM50104963 (2S,3R)-2-(cyclopropylmethylamino)-N1-hydroxy-N4-((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)-3-(3-hydroxybenzyl)succinamide::(3R)-N~2~-(cyclopropylmethyl)-N~1~-hydroxy-3-(3-hydroxybenzyl)-N~4~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-L-aspartamide::(R)-2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydroxy-benzyl)-N*4*-((3S,3aR)-2-hydroxy-indan-1-yl)-succinamide::2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydroxy-benzyl)-N*4*-(2-hydroxy-indan-1-yl)-succinamide::CHEMBL24398
SMILES ONC(=O)[C@@H](NCC1CC1)[C@@H](Cc1cccc(O)c1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12
InChI Key InChIKey=UACUZULRKJKTHE-CZYKHXBRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50104963
Affinity DataKi: 171nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataKi: 4.47E+3nMAssay Description:Affinity for Matrix metalloproteinase-9(MMP-9)More data for this Ligand-Target Pair
Affinity DataKi: 4.47E+3nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataKi: 6.30E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataKi: 3.32E+4nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of human recombinant TACE after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant MMP1 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant ADAMTS5 expressed in HEK293 cells using Abz-TESEwSRGAIY-Dpa-KK as substrate measured for 2 hrs by fluorometric analys...More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant aggrecanase 1 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant ADAMTS4 expressed in HEk293 cells using FAM-AEwLQGRPISIAK-TAMRA as substrate measured for 15 mins by fluorometric ana...More data for this Ligand-Target Pair