BDBM50105458 CHEMBL433171::N-Hydroxy-2-methyl-2-phenethylamino-3-(4-phenoxy-benzenesulfonyl)-propionamide

SMILES CC(CS(=O)(=O)c1ccc(Oc2ccccc2)cc1)(NCCc1ccccc1)C(=O)NO

InChI Key InChIKey=IXBLAZNLURBEMT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50105458   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105458(CHEMBL433171 | N-Hydroxy-2-methyl-2-phenethylamino...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105458(CHEMBL433171 | N-Hydroxy-2-methyl-2-phenethylamino...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105458(CHEMBL433171 | N-Hydroxy-2-methyl-2-phenethylamino...)
Affinity DataIC50:  2.40nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105458(CHEMBL433171 | N-Hydroxy-2-methyl-2-phenethylamino...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105458(CHEMBL433171 | N-Hydroxy-2-methyl-2-phenethylamino...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed