BDBM50105883 3-[25-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-19-(3H-imidazol-4-ylmethyl)-10-(1H-indol-3-ylmethyl)-16-naphthalen-2-ylmethyl-6,9,12,15,18,21,24-heptaoxo-1,2-dithia-5,8,11,14,17,20,23-heptaaza-cyclohexacos-22-yl]-propionic acid::CHEMBL408843

SMILES CC(=O)N[C@@H]1CSSC[C@H](NC(=O)CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(N)=O

InChI Key InChIKey=XUCSIJVANOTEDW-FFZORDHOSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105883   

TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105883(3-[25-Acetylamino-4-carbamoyl-13-(3-guanidino-prop...)
Affinity DataKi:  0.390nMAssay Description:Binding affinity against human melanocortin receptor 5 (hMC5R) (concentration of the peptide at 50% specific binding)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105883(3-[25-Acetylamino-4-carbamoyl-13-(3-guanidino-prop...)
Affinity DataKi:  0.570nMAssay Description:Binding affinity against human melanocortin receptor 4 (hMC4R) (concentration of the peptide at 50% specific binding)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105883(3-[25-Acetylamino-4-carbamoyl-13-(3-guanidino-prop...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity against human melanocortin receptor 3 (hMC3R) (concentration of the peptide at 50% specific binding)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105883(3-[25-Acetylamino-4-carbamoyl-13-(3-guanidino-prop...)
Affinity DataEC50:  0.220nMAssay Description:Increase in intracellular cAMP in CHO cells expressing human melanocortin receptor 5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed