BDBM50106856 3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 2-fluoro-ethyl ester::CHEMBL318961

SMILES CN1C2CCC1C(C(C2)c1ccc(I)cc1)C(=O)OCCF

InChI Key InChIKey=FWXXADKIJMPYFM-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50106856   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50106856(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  0.930nMAssay Description:Displacement of [3H]-CIT from dopamine transporter of rat striatal homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50106856(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  0.930nMAssay Description:Ability to displace [3H]- beta-CIT from Dopamine transporter in rat striatal homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Alcohol And Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106856(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  1.70nMAssay Description:Ability to displace [3H]- paroxetine from Serotonin transporter in rat cerebral cortical homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Alcohol And Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106856(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  4.02nMAssay Description:Displacement of [3H]-cyanoimiprimine from serotonin transporter of rat cerebral cortical homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50106856(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  116nMAssay Description:Displacement of [3H]-nisoxetine from norepinephrine transporter of rat cerebral corticex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50106856(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  173nMAssay Description:Ability to displace [3H]- nisoxetin from Norepinephrine transporter in rat cerebral cortical homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed