BDBM50107083 CHEMBL110609::[5-(2,4-Dichloro-phenyl)-1-methyl-1H-[1,2,4]triazol-3-yl]-dicyclopropylmethyl-propyl-amine

SMILES CCCN(C(C1CC1)C1CC1)c1nc(-c2ccc(Cl)cc2Cl)n(C)n1

InChI Key InChIKey=OHAPFIXJEPEEFO-UHFFFAOYSA-N

Data  3 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50107083   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences Inc

Curated by ChEMBL
LigandPNGBDBM50107083(CHEMBL110609 | [5-(2,4-Dichloro-phenyl)-1-methyl-1...)
Show SMILES CCCN(C(C1CC1)C1CC1)c1nc(-c2ccc(Cl)cc2Cl)n(C)n1
Show InChI InChI=1S/C19H24Cl2N4/c1-3-10-25(17(12-4-5-12)13-6-7-13)19-22-18(24(2)23-19)15-9-8-14(20)11-16(15)21/h8-9,11-13,17H,3-7,10H2,1-2H3
Affinity DataKi:  9nMAssay Description:Inhibition of [125I]-o-CRF binding to human Corticotrophin releasing factor receptor 1 expressed in CHO cells.More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences Inc

Curated by ChEMBL
LigandPNGBDBM50107083(CHEMBL110609 | [5-(2,4-Dichloro-phenyl)-1-methyl-1...)
Show SMILES CCCN(C(C1CC1)C1CC1)c1nc(-c2ccc(Cl)cc2Cl)n(C)n1
Show InChI InChI=1S/C19H24Cl2N4/c1-3-10-25(17(12-4-5-12)13-6-7-13)19-22-18(24(2)23-19)15-9-8-14(20)11-16(15)21/h8-9,11-13,17H,3-7,10H2,1-2H3
Affinity DataKi:  9.20nMAssay Description:Inhibition of [125I][Tyr0]-sauvagine binding to human Corticotropin releasing factor receptor 1 expressed in mouse fibroblast Ltk- cells More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Neurocrine Biosciences Inc

Curated by ChEMBL
LigandPNGBDBM50107083(CHEMBL110609 | [5-(2,4-Dichloro-phenyl)-1-methyl-1...)
Show SMILES CCCN(C(C1CC1)C1CC1)c1nc(-c2ccc(Cl)cc2Cl)n(C)n1
Show InChI InChI=1S/C19H24Cl2N4/c1-3-10-25(17(12-4-5-12)13-6-7-13)19-22-18(24(2)23-19)15-9-8-14(20)11-16(15)21/h8-9,11-13,17H,3-7,10H2,1-2H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for human Corticotropin releasing factor receptor 2More data for this Ligand-Target Pair