BDBM50107240 CHEMBL344432::[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-[2-(pyridin-2-yloxy)-ethyl]-amine

SMILES COc1cccc2C(CCCNCCOc3ccccn3)CCCc12

InChI Key InChIKey=HETKYUVAGHVYTA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50107240   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50107240(CHEMBL344432 | [3-(5-Methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  0.230nMAssay Description:Binding affinity of the compound was determined on human cloned 5-hydroxytryptamine 1A receptor transfected in human cell lines(He La)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50107240(CHEMBL344432 | [3-(5-Methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  0.540nMAssay Description:Binding was determined on 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50107240(CHEMBL344432 | [3-(5-Methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  0.550nMAssay Description:Binding affinity was determined on human cloned alpha1a adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50107240(CHEMBL344432 | [3-(5-Methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  12.7nMAssay Description:Binding affinity of the compound towarda alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50107240(CHEMBL344432 | [3-(5-Methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  26.4nMAssay Description:Binding affinity was determined on human cloned alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50107240(CHEMBL344432 | [3-(5-Methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi: >850nMAssay Description:Binding affinity towards dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed