BDBM50107559 CHEMBL168904::N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)-ethoxy]-2-propyl-5-p-tolyl-pyrimidin-4-yl}-4-tert-butyl-benzenesulfonamide

SMILES CCCc1nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c(c(OCCOc2ncc(Br)cn2)n1)-c1ccc(C)cc1

InChI Key InChIKey=BHSAHNPXJBATRX-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107559   

TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50107559(CHEMBL168904 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Show SMILES CCCc1nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c(c(OCCOc2ncc(Br)cn2)n1)-c1ccc(C)cc1
Show InChI InChI=1S/C30H34BrN5O4S/c1-6-7-25-34-27(36-41(37,38)24-14-12-22(13-15-24)30(3,4)5)26(21-10-8-20(2)9-11-21)28(35-25)39-16-17-40-29-32-18-23(31)19-33-29/h8-15,18-19H,6-7,16-17H2,1-5H3,(H,34,35,36)
Affinity DataIC50: 1.60nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membrane.More data for this Ligand-Target Pair