BDBM50107904 (3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-dimethylamino-naphthalene-1-sulfonyl)-pyrrolidine-2-carbonyl]-3-methyl-hexahydro-pyrrolo[3,2-b]pyrrol-2-one::4-Cyclopropanecarbonyl-1-[1-(5-dimethylamino-naphthalene-1-sulfonyl)-pyrrolidine-2-carbonyl]-6-methyl-hexahydro-cyclopenta[b]pyrrol-5-one::CHEMBL299435

SMILES C[C@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H]2CCCN2S(=O)(=O)c2cccc3c(cccc23)N(C)C)N(C(=O)C2CC2)C1=O

InChI Key InChIKey=VSHOGRNAHIXNQF-XVYJZYCRSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50107904   

TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)
Affinity DataKi:  20nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards Human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)
Affinity DataIC50:  340nMAssay Description:Concentration required for inhibition of human cytomegalo virus (HCMV) protease activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)
Affinity DataIC50:  340nMAssay Description:Tested in vitro for inhibitory activity of the compound against ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required for 50% Acetylcholinesterase inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human cytomegalovirus protease in HCMV pNA assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)
Affinity DataIC50: >2.00E+5nMAssay Description:Concentration required for 50% thrombin inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed