BDBM50108444 1-(1-Phenyl-2-pyrrolidin-1-yl-ethyl)-3-(4-trifluoromethoxy-phenyl)-1H-pyridin-2-one::CHEMBL61426

SMILES FC(F)(F)Oc1ccc(cc1)-c1cccn(C(CN2CCCC2)c2ccccc2)c1=O

InChI Key InChIKey=AIGBFJAZWRJQLT-UHFFFAOYSA-N

Data  3 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108444   

TargetDelta-type opioid receptor(Homo sapiens (Human))
AstraZeneca R&D Mölndal

Curated by ChEMBL
LigandPNGBDBM50108444(1-(1-Phenyl-2-pyrrolidin-1-yl-ethyl)-3-(4-trifluor...)
Show SMILES FC(F)(F)Oc1ccc(cc1)-c1cccn(C(CN2CCCC2)c2ccccc2)c1=O
Show InChI InChI=1S/C24H23F3N2O2/c25-24(26,27)31-20-12-10-18(11-13-20)21-9-6-16-29(23(21)30)22(17-28-14-4-5-15-28)19-7-2-1-3-8-19/h1-3,6-13,16,22H,4-5,14-15,17H2
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards delta opioid receptor by the displacement of [125I]-DeltorphinMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca R&D Mölndal

Curated by ChEMBL
LigandPNGBDBM50108444(1-(1-Phenyl-2-pyrrolidin-1-yl-ethyl)-3-(4-trifluor...)
Show SMILES FC(F)(F)Oc1ccc(cc1)-c1cccn(C(CN2CCCC2)c2ccccc2)c1=O
Show InChI InChI=1S/C24H23F3N2O2/c25-24(26,27)31-20-12-10-18(11-13-20)21-9-6-16-29(23(21)30)22(17-28-14-4-5-15-28)19-7-2-1-3-8-19/h1-3,6-13,16,22H,4-5,14-15,17H2
Affinity DataIC50: 34nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
AstraZeneca R&D Mölndal

Curated by ChEMBL
LigandPNGBDBM50108444(1-(1-Phenyl-2-pyrrolidin-1-yl-ethyl)-3-(4-trifluor...)
Show SMILES FC(F)(F)Oc1ccc(cc1)-c1cccn(C(CN2CCCC2)c2ccccc2)c1=O
Show InChI InChI=1S/C24H23F3N2O2/c25-24(26,27)31-20-12-10-18(11-13-20)21-9-6-16-29(23(21)30)22(17-28-14-4-5-15-28)19-7-2-1-3-8-19/h1-3,6-13,16,22H,4-5,14-15,17H2
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity towards mu opioid receptor by the displacement of [125I]-EnkephalinMore data for this Ligand-Target Pair