BDBM50110927 1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester::CHEMBL285975::methyl 1-(4-chlorobenzyl)-5-(methylsulfonyl)-1H-indole-2-carboxylate

SMILES COC(=O)c1cc2cc(ccc2n1Cc1ccc(Cl)cc1)S(C)(=O)=O

InChI Key InChIKey=UBZBOEWMQPWUKB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50110927   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50110927(1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibitory effect on Prostaglandin G/H synthase 2 activity was evaluated in human whole blood as LPS-induced PGE-2 generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50110927(1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50110927(1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50110927(1-(4-Chloro-benzyl)-5-methanesulfonyl-1H-indole-2-...)
Affinity DataIC50:  650nMAssay Description:Inhibition of PGE-2 generation in LPS-stimulated human monocytes (Prostaglandin G/H synthase 2 cell assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed