BDBM50112495 3-(3-{4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-trifluoromethyl-phenylamino}-propenyl)-benzamidine::CHEMBL26500

SMILES CC(=N)N1CCC(CC1)Oc1ccc(NC\C=C\c2cccc(c2)C(N)=N)cc1C(F)(F)F

InChI Key InChIKey=TYGCRUSCHGBIBW-VCZNOJSUSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112495   

TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112495(3-(3-{4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-tr...)
Affinity DataKi:  0.880nMAssay Description:Competitive inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112495(3-(3-{4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-tr...)
Affinity DataKi:  50nMAssay Description:Competitive inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112495(3-(3-{4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-tr...)
Affinity DataKi:  2.14E+3nMAssay Description:Competitive inhibition of coagulation factor IIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed