BDBM50112679 2-Benzo[1,3]dioxol-5-yl-4-pentyloxy-2H-chromene-3-carboxylic acid::CHEMBL293702

SMILES CCCCCOC1=C(C(Oc2ccccc12)c1ccc2OCOc2c1)C(O)=O

InChI Key InChIKey=ARAWMFVXKCGSKN-UHFFFAOYSA-N

Data  3 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112679   

TargetEndothelin-1 receptor(RAT)
Shionogi & Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50112679(2-Benzo[1,3]dioxol-5-yl-4-pentyloxy-2H-chromene-3-...)
Show SMILES CCCCCOC1=C(C(Oc2ccccc12)c1ccc2OCOc2c1)C(O)=O
Show InChI InChI=1S/C22H22O6/c1-2-3-6-11-25-21-15-7-4-5-8-16(15)28-20(19(21)22(23)24)14-9-10-17-18(12-14)27-13-26-17/h4-5,7-10,12,20H,2-3,6,11,13H2,1H3,(H,23,24)
Affinity DataIC50: 29nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(RAT)
Shionogi & Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50112679(2-Benzo[1,3]dioxol-5-yl-4-pentyloxy-2H-chromene-3-...)
Show SMILES CCCCCOC1=C(C(Oc2ccccc12)c1ccc2OCOc2c1)C(O)=O
Show InChI InChI=1S/C22H22O6/c1-2-3-6-11-25-21-15-7-4-5-8-16(15)28-20(19(21)22(23)24)14-9-10-17-18(12-14)27-13-26-17/h4-5,7-10,12,20H,2-3,6,11,13H2,1H3,(H,23,24)
Affinity DataIC50: 29nMAssay Description:Ability to displace [125I]-ET-1 from the rat endothelin A receptor expressed in rat aorta smooth muscle cells.More data for this Ligand-Target Pair
TargetEndothelin receptor type B(Sus scrofa)
Shionogi & Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50112679(2-Benzo[1,3]dioxol-5-yl-4-pentyloxy-2H-chromene-3-...)
Show SMILES CCCCCOC1=C(C(Oc2ccccc12)c1ccc2OCOc2c1)C(O)=O
Show InChI InChI=1S/C22H22O6/c1-2-3-6-11-25-21-15-7-4-5-8-16(15)28-20(19(21)22(23)24)14-9-10-17-18(12-14)27-13-26-17/h4-5,7-10,12,20H,2-3,6,11,13H2,1H3,(H,23,24)
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity to endothelin B receptor measured by inhibition of [125I]-ET-3 binding recombinant pig ET-B receptor expressed in COS-7 cellsMore data for this Ligand-Target Pair