BDBM501135 (R)-7-((6-(2- (dimethylami- no)ethyl)-5- (tetrahydrofuran- 3-yl)pyridin- 2-yl)amino)-3- (1-methyl-1H- pyrrolo[2,3- b)pyridin-4- yl)-2,3- dihydro-1H- pyrrolo[3,4- c]pyridin-1- one::US11021481, Compound I-807::US11078201, Compound I-807::US11548890, Compound I-807
SMILES CN(C)CCc1nc(Nc2cnc(c3CNC(=O)c23)-c2ccnc3n(C)ccc23)ccc1[C@@H]1CCOC1
InChI Key InChIKey=CWNRDNDDTUMAOX-QGZVFWFLSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 501135
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair