BDBM50113909 2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-6-[3-(4-methyl-imidazol-1-yl)-phenoxy]-isonicotinic acid::CHEMBL79828

SMILES Cc1cn(cn1)-c1cccc(Oc2cc(cc(Oc3cc(ccc3O)C(N)=N)n2)C(O)=O)c1

InChI Key InChIKey=LMYRFALJJDTPPD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50113909   

TargetCoagulation factor X(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113909(2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-6-[3-(4-meth...)
Affinity DataKi:  13nMAssay Description:Inhibition of human Coagulation factor X was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113909(2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-6-[3-(4-meth...)
Affinity DataKi:  13nMAssay Description:Inhibitory constant against human coagulation factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50113909(2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-6-[3-(4-meth...)
Affinity DataKi:  160nMAssay Description:Inhibitory constant against bovine trypsin for general specificity against serine proteasesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50113909(2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-6-[3-(4-meth...)
Affinity DataKi:  650nMAssay Description:Inhibitory constant against human coagulation factor II (thrombin) for selectivity within coagulation cascadeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed