BDBM50114703 CHEMBL287560::N-[2-(5-Methoxy-2-phenyl-benzofuran-3-yl)-ethyl]-acetamide
SMILES COc1ccc2oc(c(CCNC(C)=O)c2c1)-c1ccccc1
InChI Key InChIKey=YZKUZJRTQSAJNG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50114703
Affinity DataKi: 0.0100nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
Affinity DataKi: 0.0100nMAssay Description:Binding affinity on human melatonin receptor type 1A stably transfected in human embryonic kidney (HEK 293) using 2-[125I]-iodomelatonin as radioliga...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by ChEMBL
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by ChEMBL
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
Affinity DataEC50: 0.170nMAssay Description:Intrinsic activity evaluated on [35S]-GTP -gamma-S binding in Chinese hamster ovarian (CHO) cells, stably expressing human Melatonin receptor type 1AMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by ChEMBL
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by ChEMBL
Affinity DataEC50: 0.0960nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair