BDBM50115102 (1-Hydroxy-1-phosphono-ethyl)-phosphonic acid::CHEMBL871::Didronel::ETIDRONATE::Etidronic Acid

SMILES CC(O)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=DBVJJBKOTRCVKF-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50115102   

TargetType IV secretion-like conjugative transfer relaxase protein TraI(Escherichia coli (strain SMS-3-5 / SECEC))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50115102((1-Hydroxy-1-phosphono-ethyl)-phosphonic acid | CH...)
Affinity DataKi:  3nMAssay Description:Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInositol monophosphatase 1(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50115102((1-Hydroxy-1-phosphono-ethyl)-phosphonic acid | CH...)
Affinity DataIC50:  1.10E+5nMAssay Description:Concentration required for 50% inhibition of Inositol monophosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50115102((1-Hydroxy-1-phosphono-ethyl)-phosphonic acid | CH...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed