BDBM50115640 (-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,4a-diaza-tribenzo[a,c,e]cycloheptene::CHEMBL113238
SMILES COc1cccc2Cc3ccccc3[C@@H]3CN(C)CCN3c12
InChI Key InChIKey=GZXNMNCAWGIAAW-KRWDZBQOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50115640
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.390nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.75nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:The binding affinity of the compound at the Dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:The binding affinity of the compound at the Dopamine receptor D4 determined using [3H]-YM-09151-2More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 1D receptor was determined using [3H]-5-CTMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:The binding affinity of the compound at the Dopamine receptor D3 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 255nMAssay Description:The binding affinity of the compound at the 5-hydroxytryptamine 1A receptor determined using [3H]-5-CTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 1.65E+3nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 3 receptor was determined using [3H]-LY-278,584More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:The binding affinity of the compound at the 5-HT reputake sites determined using competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.86E+3nMAssay Description:The binding affinity of the compound at the Norepinephrin transpoter reputake sites determined using competition binding assayMore data for this Ligand-Target Pair