BDBM50115667 CHEMBL111953::[4-(4-Hydroxy-3-isopropyl-5-phenylethynyl-benzyl)-3,5-dimethyl-phenoxy]-acetic acid(NH-1)

SMILES CC(C)c1cc(Cc2c(C)cc(OCC(O)=O)cc2C)cc(C#Cc2ccccc2)c1O

InChI Key InChIKey=NSMJTCRIXMAXDP-UHFFFAOYSA-N

Data  2 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50115667   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115667(CHEMBL111953 | [4-(4-Hydroxy-3-isopropyl-5-phenyle...)
Affinity DataKd:  490nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115667(CHEMBL111953 | [4-(4-Hydroxy-3-isopropyl-5-phenyle...)
Affinity DataEC50:  500nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115667(CHEMBL111953 | [4-(4-Hydroxy-3-isopropyl-5-phenyle...)
Affinity DataKd:  37nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed