BindingDB logo
myBDB logout

BDBM50115870 2-(3-Ethoxy-2-hydroxy-phenyl)-1H-benzoimidazole-5-carboxamidine::CHEMBL64838

SMILES: CCOc1cccc(-c2nc3ccc(cc3[nH]2)C(N)=N)c1O

InChI Key: InChIKey=LNZOGIFQFBYRHJ-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50115870   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50115870
PNG
(2-(3-Ethoxy-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Show SMILES CCOc1cccc(-c2nc3ccc(cc3[nH]2)C(N)=N)c1O
Show InChI InChI=1S/C16H16N4O2/c1-2-22-13-5-3-4-10(14(13)21)16-19-11-7-6-9(15(17)18)8-12(11)20-16/h3-8,21H,2H2,1H3,(H3,17,18)(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
700n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of urokinase-type plasminogen activator


Bioorg Med Chem Lett 12: 2019-22 (2002)


Article DOI: 10.1016/s0960-894x(02)00311-6
BindingDB Entry DOI: 10.7270/Q237782T
More data for this
Ligand-Target Pair
Plasminogen


(Homo sapiens (human))
BDBM50115870
PNG
(2-(3-Ethoxy-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Show SMILES CCOc1cccc(-c2nc3ccc(cc3[nH]2)C(N)=N)c1O
Show InChI InChI=1S/C16H16N4O2/c1-2-22-13-5-3-4-10(14(13)21)16-19-11-7-6-9(15(17)18)8-12(11)20-16/h3-8,21H,2H2,1H3,(H3,17,18)(H,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.60E+3n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of plasmin


Bioorg Med Chem Lett 12: 2019-22 (2002)


Article DOI: 10.1016/s0960-894x(02)00311-6
BindingDB Entry DOI: 10.7270/Q237782T
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (human))
BDBM50115870
PNG
(2-(3-Ethoxy-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Show SMILES CCOc1cccc(-c2nc3ccc(cc3[nH]2)C(N)=N)c1O
Show InChI InChI=1S/C16H16N4O2/c1-2-22-13-5-3-4-10(14(13)21)16-19-11-7-6-9(15(17)18)8-12(11)20-16/h3-8,21H,2H2,1H3,(H3,17,18)(H,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.20E+3n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of tissue-type plasminogen activator


Bioorg Med Chem Lett 12: 2019-22 (2002)


Article DOI: 10.1016/s0960-894x(02)00311-6
BindingDB Entry DOI: 10.7270/Q237782T
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50115870
PNG
(2-(3-Ethoxy-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Show SMILES CCOc1cccc(-c2nc3ccc(cc3[nH]2)C(N)=N)c1O
Show InChI InChI=1S/C16H16N4O2/c1-2-22-13-5-3-4-10(14(13)21)16-19-11-7-6-9(15(17)18)8-12(11)20-16/h3-8,21H,2H2,1H3,(H3,17,18)(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.80E+3n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of Coagulation factor X


Bioorg Med Chem Lett 12: 2019-22 (2002)


Article DOI: 10.1016/s0960-894x(02)00311-6
BindingDB Entry DOI: 10.7270/Q237782T
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50115870
PNG
(2-(3-Ethoxy-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Show SMILES CCOc1cccc(-c2nc3ccc(cc3[nH]2)C(N)=N)c1O
Show InChI InChI=1S/C16H16N4O2/c1-2-22-13-5-3-4-10(14(13)21)16-19-11-7-6-9(15(17)18)8-12(11)20-16/h3-8,21H,2H2,1H3,(H3,17,18)(H,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.10E+4n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of thrombin


Bioorg Med Chem Lett 12: 2019-22 (2002)


Article DOI: 10.1016/s0960-894x(02)00311-6
BindingDB Entry DOI: 10.7270/Q237782T
More data for this
Ligand-Target Pair