BDBM50117488 CHEMBL217362::H-His-Ala-Lys-Arg-Arg-Leu-Ile-Phe-NH2

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=YHVVVHLDNQXTEZ-GXTUSLNOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50117488   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50117488(CHEMBL217362 | H-His-Ala-Lys-Arg-Arg-Leu-Ile-Phe-N...)
Affinity DataIC50:  140nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50117488(CHEMBL217362 | H-His-Ala-Lys-Arg-Arg-Leu-Ile-Phe-N...)
Affinity DataIC50:  50nMAssay Description:Binding affinity to Cyclin A by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50117488(CHEMBL217362 | H-His-Ala-Lys-Arg-Arg-Leu-Ile-Phe-N...)
Affinity DataIC50:  39nMAssay Description:In vitro inhibition of CDK2-cyclin A kinase activity on retinoblastoma proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed